Meer onderwerpen uit de bijeenkomst van ATA (American Thyr. Ass.) welke is gehouden Okt./Nov. 2014
ATA Highlights New Thyroid Cancer Research
The impact of RAI on long-term outcomes, potential combination strategies, molecular profiling, and novel therapeutics for patients with thyroid cancer were among some of the topics highlighted at the 2014 ATA Annual Meeting.
http://www.onclive.com/conference-cover ... r-Research
Molecular Diagnostics Focus on Thyroid Nodule Classification
New data being presented at the 84th Annual Meeting of the American Thyroid Association show promise for two molecular tests that help identify indeterminate thyroid nodules as either benign or malignant.
http://www.onclive.com/conference-cover ... sification
Novel NGS Test May Enhance Diagnosis and Management of Indeterminate Thyroid Nodules
A next-generation sequencing assay has shown promise as a new tool to aid in the diagnosis and treatment of indeterminate thyroid nodules.
http://www.onclive.com/conference-cover ... id-Nodules
Next-Generation Sequencing Effectively Detects Cancer in Thyroid Nodules
The ThyroSeq v2 next-generation sequencing assay was highly accurate at diagnosing cancer in thyroid nodules with follicular neoplasm or those suspected of follicular neoplasm cytology.
http://www.onclive.com/conference-cover ... id-Nodules
Novel Therapeutic Target Identified in Aggressive Thyroid Cancers
In vivo models for two aggressive thyroid cancers have shown that downregulation of miR-30a-5p leads to overexpression of LOX, a target which appears amenable to treatment with β-aminopropionitrile fumarate.
http://www.onclive.com/conference-cover ... id-Cancers
New Assay Effectively Detects Circulating BRAFV600E in Patients With Papillary Thyroid Cancer
The detection of BRAFV600E in patients with papillary thyroid cancer using a blood-based assay was shown to be feasible in a cohort of patients undergoing thyroidectomy.
http://www.onclive.com/conference-cover ... oid-Cancer
Vitamin D Levels Predict Hypocalcemia Following Thyroid Cancer Treatment
Preoperative vitamin D deficiency is associated with postoperative symptomatic hypocalcemia in patients with thyroid cancer undergoing total thyroidectomy plus central compartment neck dissection.
http://www.onclive.com/conference-cover ... -Treatment
Disease-Related Variables Predictive of Outcomes With Sorafenib in DTC
Numerous disease-related variables could serve as prognostic and predictive factors for treatment outcomes with sorafenib in patients with radioactive iodine-refractory differentiated thyroid cancer.
http://www.onclive.com/conference-cover ... nib-in-DTC
PD-1 Immunotherapies Induce Painless Thyroiditis in Patients With Metastatic Malignancies
Treatment with PD-1 immunotherapy across various oncology clinical trials has been associated with the induction of painless thyroiditis, characterized by transient thyrotoxicosis and hypothyroidism, in patients with metastatic malignancies
http://www.onclive.com/conference-cover ... lignancies
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